Absolutely sure.

I raise Bills of Lading, and legalise Bills of Lading as part of my job. Like these:
http://fujita.weblike.jp/msc_BL_3.jpg
A ships manifest covers ALL of the cargo on board. It's simply a list of individual shipments on board, much as an aircraft passenger manifest is a list of the passengers; however, commercial passenger flights also take cargo on board, and each of those consignments, whilst appearing on a cargo manifest, also have it's own Air Waybill, which serves exactly the same purpose as a marine Bill of Lading.
A Bill of Lading covers an individual shipment. It details the number of packages in the consignment, what each package contains, the gross weight etc.
A Bill of Lading IS a legal document. It is the legal title to the goods. Without the
ORIGINAL BL, the consignee for the goods cannot even take possession of them because the shipping line won't release them.
There are also Multimodal Bills of Lading, which will cover a consignments entire journey, even if the method of shipment changes (IE goes by vessel from UK to Jordan, then by truck from Jordan into Iraq), but the rule remains that if the receiver of the goods doesn't have that original BL...they ain't getting their hands on the goods, even if they've paid for them in full in advance. That's how legal a document it is.
Individual Bills of Lading predate vessel manifests by quite some margin.
There are also differences between Master Bills of Lading (issued by the shipping line) and House Bills of Lading (issued by a private company), but I won't bore you with that