For about 25 years I used Nikon manual focus film bodies and lenses, and loved all that gear, but when I decided to finally go digital I realised that Nikon DSLRs had absolutely nothing whatsoever to do with the FE2 I was giving up so brand loyalty was a nonsense, and my lenses (which I was having to sell anyway) wouldn't have been very much use on the entry level bodies I was thinking about anyway.
In the end I went with Canon because their system seemed to make more sense to me, I knew many more people with their gear (and lenses I could borrow) and the controls and menus etc all felt right. No regrets at all.