Very rarely when permissible I have no option but to use on camera flash. Last night was such an occasion, available light was not sufficient and flash couldn't be bounced. I shot with on camera flash, using pre-flash. When editing I noticed the pupils of all but one were smaller, and had no red eye. In every shot one person still had enlarged pupils and they were a dull red. Easy to edit out, but I'm curious why. Has anyone ever come across this before and do they know why?
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