Very easy to do without a meter. The way I do it is this.
Start with the front light (HiLite off) because that's the one I like to set for a certain f/number. Get that looking right on the LCD and check the histogram/blinkies to confirm it's right. Now switch on the HiLite flashes as well, and turn them up until blinkies just begin to flash.
In theory, you should now be set, but you'll probably want to do a bit of tweaking because in the average room the HiLight will chuck out a lot of light, some of which will bounce around the room and find its way to the front of the subject. So turn the front light down a bit if needs be.
As Garry says, the thing that commonly ruins this style of lighting is whacking up the background. It only needs to be just over-exposed - blown is blown, whether it's 1% over or nuked.
Tips: to reduce flare, screen off all areas of the background that are not actually in shot.
HiLites are pretty evenly lit if you do it right, but if the corners are a bit grey, leave them and just make sure it's optimum around the central subject. You can clean up the edges in post processing.
Top help avoid hot-spots, point the lights towards the back/centre and make sure no light is able to shine directly on to the front surface. Put a little cardboard flag on the flash to shade it if necessary.
Wrap is part of this 'look' - basically the background reflecting off the cheeks and neck. Moderate this to taste by moving the subject further/closer from the background.