Not sure about Nikon's flash system, but with Canon firing a flash at a dark and insignificant subject with a background of nothingness is likely to fire the flash at maximum and give you a white (or grey) blob against the darkness. At least I've only tried it once and that was the result for me.
As well as setting exposure controls and focus manually I think you will also need to set the flash manually as well, varying power and aperture to suit your pre-selected shooting distance. If you want to fire a burst then obviously you can't expect the flash to fire out multiple full power pops in quick succession, so factor that into your deliberations.
Your flash may well support support FP Sync, but I think as other have said that you'd be best served by shooting within the flash sync speed and letting the flash duration freeze your subject.
I just tried an experiment with my 580EX set to 1/8 power at 35mm coverage and that required 1/250, f/5.6, 200 ISO for a 3m range to give me four well exposed shots in quick succession. I then had five black frames before the flash recovered for the tenth and final frame in the burst.
I'm sure it's possible. It just needs a bit of maths on the camera/flash settings.