Yes, it certainly is very worthwhile. When I went (a few years ago) it was challenging but not impossible to use a tripod in the busier areas. This year they are organising a ticket system for the central areas during certain hours, which may help.
When I visited I shot on film with ISO800 film, and a very old Leica Digilux 2 that is limited to ISO400. So if you can go to a much higher ISO then you have a good chance. I suggest you just go to enjoy the event and if you get some images, consider it a bonus.Thanks.
On these quick weekend visits I usually take just the Fuji X30. I'm unlikely to have a tripod with me but could drag along the D7100 (not renowned for great ISO quality) and 35mm 1.8 or 16-85 3.5/5.6.
Handholding (I don't have the shakes yet) do you think I would get away any of the above.
Regards
Neil