Seriously though... in real life, who calculates it? I mean, once you know the formulas to do so, it's easy enough, but who actually gets a calculator out when shooting? All anyone really needs to know is that the closer you focus, the less the DOF is, and the further away the focused object is, the greater it is. That it also
increases decreases with focal length
Calm down Hoppy, before your head explodes 
.. I know that's not actually true, but that's the EFFECT, and that's all people really need to know. Also, making the aperture smaller increases it. and making it larger decreases it.
None of that is scientific, but knowing those things will allow you to work. You will know how to use DOF, and you will not be a worse photographer for not knowing the maths that allow you to calculate it precisely.
Can I do the maths? Yes. Do I bother when out shooting? Of course not!

Who does?
I wouldn't teach this on a degree: I'd explain that there are ways to calculate these things precisely, and recommend a book or two, then they can if they want... but most people (myself included) would just rather understand the practical application of these principles, and go shooting instead
I can roughly guess that for instance... A 50mm (on full frame) lens focused at 1 meter wide open (1.8) would give me less than 10cm DOF.... and the same lens wide open focused at something 10 metres away would give me around 5 metres DOF.... and at infinity, anything closer than around 10 metres would start to get soft. I did no calculations there... that's from experience. I'm not even going to bother working out whether I'm right or not... it's 7a.m.. and I've not had coffee yet

I bet anyone on here though £10 that I'm close enough with those guesstimates to work effectively on the field... plus.... I'd just use my DOF preview anyway.
Go out there.... find out PRACTICALLY and get used to how your equipment works instead of sitting there solving maths problems!!
Just my advice of course. You may like solving maths problems more than shooting.. in which case.. carry on