That's difficult, different people have different ideas of what a "significant increase in IQ" is.
I've tried a 400mm f/5.6L it seems more contrasty than my 100-400, but when my 100-400 is stopped down to f/7.1 or f/8 it's sharpness is pretty darn close to the prime. When you compare wide open the difference in contrast is a bit more, but the sharpness of the 100-400 is still not too far off.
To be honest, it's something you have to try for yourself to really see what the difference is.
Some rental places offer a delivery service (Stewart on here runs lensesforhire.com, I believe they'll post a lens to you).