This issue is quite common when focusing at night, I had it last week and in the end opened up the aperture as wide as possible and focused manually and then did what I needed to do, the auto-focus can get confused if theres no clear difference in textures. E.g. I found it really difficult to focus on tree branches when it was late at night, no big deal as it was to be expected but I just needed to focus manually.With a low aperture you might not be able to see as well so open it up as wide as possible and focus though that, then make the necessary ISO, shutter and aperture adjustments.