My parents have been considering exactly this last week, the current roof is leaking in two places and they've been told it's because the seals have worn and the panels are slipping. For a solid tiled roof they have been getting quotes of £12,500 and a very pricey £19,000 for a 16m² conservatory, although I think the aesthetics and supposed better temp regulation of a tiled roof is appealing. The latter and more expensive company were saying repairs aren't possible because you can't get parts for them any more, presumably meaning the seals.
There would be a structural engineer involved because of the additional weight and presumably a building warrant because of this. They said it would be three days work, which seems impressive considering what is involved: Wood framing, sarking boards, installing tiles, insulation, plasterboard, electrics and lights, plastering, boxing off exposed frame sitting on top of windows.
I've started looking into myself and it would seem that you can quite easily remove the panels, clean them and silicone seal them back in place, so I'm going to look into that first and see if it's the same procedure for their conservatory. At the very least it would take the pressure off from rushing into such a big cost.