Is it for the M100 in your profile? You could use Canon's EF-EOS M adapter to mount Canon EF (SLR) lenses, which will autofocus.
Adapters for lenses from other systems will generally be manual focus.
There are a few clever adapters for some other mirrorless cameras (e.g. Sony) that allow some manual focus lenses (e.g. Leica M) to be autofocused, but I don't know if anyone has made one of these for EOS M cameras.